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Authentic Tex-Mex with San Antonio Soul

Family-owned for three generations, Mesquite Cantina brings the bold flavors of South Texas and Northern Mexico to the heart of San Antonio. Our recipes blend time-honored traditions with local ingredients, all prepared over our signature mesquite wood grill. Every dish tells a story of our border heritage, just as every meal shared here becomes part of yours.


Signature Dishes

Mesquite Grilled Fajitas
Marinated skirt steak or chicken charred over native mesquite wood, served with hand-pressed tortillas, roasted peppers, and house-made salsa fresca.

Chile Relleno San Antonio
Poblano pepper stuffed with queso fresco and Monterey Jack, lightly battered and topped with our smoky ranchero sauce.

Cochinita Pibil Tacos
Slow-roasted achiote-marinated pork served on blue corn tortillas with pickled red onions and habanero crema.

Enchiladas Verdes
Hand-rolled chicken enchiladas smothered in tangy tomatillo sauce, topped with crema fresca and cotija cheese.

Texas Campfire Queso
Our legendary blend of melted cheeses, roasted green chiles, and mesquite-smoked brisket served with fresh tortilla chips.

Abuela's Tres Leches
A family recipe passed down through generations – vanilla sponge cake soaked in three milks and topped with fresh seasonal fruit.


Hours of OperationMonday - Thursday: 11:00 AM - 10:00 PM
Friday - Saturday: 11:00 AM - 11:00 PM
Sunday: 10:00 AM - 9:00 PM

Free parking available in our private lot off Alamo Street. Additional street parking available on Brooklyn Avenue. Valet service offered Friday and Saturday evenings ($5).